Migration Analysis

What is the objective of migration analysis for substances and materials that come into contact with food?

Migration analysis for substances and materials that come into contact with food is performed to determine whether harmful substances transfer from these materials into food. This analysis is of great importance for public health, food safety, and regulatory compliance.

Migration, which can occur with materials such as plastic, metal, ceramics, rubber, and paper, can affect the quality of food and have negative impacts on human health. For this reason, migration tests are of great importance in food production and packaging.

Methods of Migration Analysis

In migration analysis, the material is first brought into contact with a food simulant. This allows for the simulation of migration under realistic food conditions. During the analysis, parameters such as temperature, time, and pH value are meticulously controlled.

Subsequently, the resulting extract is analyzed using advanced analytical techniques such as chromatography (GC, HPLC) and mass spectrometry.

Regulations and Standards

• Specific Migration [2,2-Bis(4-hydroxyphenyl)propane (Bisphenol A)] Analysis – EN 14372
• Specific Migration – Phthalate Determination – EN 13130-1 Agilent App Note
• Specific Migration – Determination of Primary Aromatic Amines (PAA) – EUR 24815 EN 2011
• Specific Migration Formaldehyde Analysis –EN 13130-23, EN 645
• Specific Migration – Determination of Elements (Aluminium (Al), Copper (Cu), Barium (Ba), Zinc (Zn), Iron (Fe), Cobalt (Co), Lithium (Li), Manganese (Mn), Nickel (Ni)) – ISO 17294-1, BS EN 13130-1
• Specific Migration – Element Determination; (Antimony (Sb); Arsenic (As); Mercury (Hg); Europium (Eu); Gadolinium (Gd); Cadmium (Cd); Chromium (Cr); Lead (Pb); Lanthanum (La); Terbium (Tb); Sodium (Na); Potassium (K); Magnesium (Mg); Calcium (Ca) –EN 13130-1, NMKL 186
• Determination of Specific Migration of Ammonium – TS 7159
• Overall Migration Analysis – Modified Polyphenylene Oxide (MPPO) – EN 1186-13 Method B, EN 14338
• Overall Migration Analysis for Volatile Food Simulants Method 1 – Total Immersion – EN 1186-1, EN 1186-3 Method 1
• Overall Migration Analysis for Volatile Food Simulants Method 5 – Filling Method –EN 1186-1, EN 1186-3 Method 5
• Overall Migration Analysis for Volatile Food Simulants Method 2 – Cell Method – EN 1186-1, EN 1186-3 Method 2
• Overall Migration Analysis for Volatile Food Simulants Method 3 – Pouch Method / Method 4 – Inverted Pouch Method – EN 1186-1, EN 1186-3 Method 4, EN 1186-1, EN 1186-3 Method 3/ Method 4
• Overall Migration Analysis Method 1 – Total Immersion (in vegetable oils) – EN 1186-2, EN 1186-1 Method -1
• Specific Migration – Elemental Determination (Lithium (Li), Beryllium (Be), Vanadium (V), Cobalt (Co), Nickel (Ni), Arsenic (As), Molybdenum (Mo), Silver (Ag), Cadmium (Cd), Tin (Sn), Mercury (Hg), Lead (Pb), Thallium (Tl), Magnesium (Mg), Aluminium (Al), Titanium (Ti), Chromium (Cr), Manganese (Mn), Iron (Fe), Copper (Cu), Zinc (Zn), Barium (Ba), Antimony (Sb)) – Metals and Alloys in Food Contact Materials and Articles

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