Animal health is of great importance for the sustainability of agriculture and the food industry as well as for public health. However, proof of the effectiveness and safety of veterinary medicinal products requires that these products be tested before they are launched. In this context, In vivo tests carried out in the context of Good Laboratory Practice (GLP) are an indispensable component of the development of veterinary medicines.
What are in vivo tests for veterinary medicines?
In-vivo tests are studies in which veterinary medicinal products are used on live animals to assess parameters such as efficacy, safety and bioavailability. These tests determine whether the drug has the desired effect and what possible side effects can occur.
What is GLP and why is it important?
GLP (Good Laboratory Practice) is an international quality standard for the planning, implementation, monitoring, recording, reporting and archiving of work in laboratories. GLP ensures transparency and accuracy, especially in critical tests such as safety assessments.
Veterinary Medicines Tests performed according to GLP standards:
- Ensure scientific validity
- They are recognized by national and international supervisory authorities
- They speed up approval procedures
- Minimize animal health and public health risks
Main In-Vivo Tests for Veterinary Medicines
In the development process of veterinary medicinal products, various in-vivo tests are carried out for different purposes:
🔬 Effectiveness Tests: The effectiveness of the drug against the target disease or infection is measured.
🔬 Toxicity Tests: The safety profile of the drug is determined by evaluating acute, subchronic or chronic toxicity.
🔬 Pharmacokinetic and bioavailability studies: The absorption, distribution, metabolism and excretion of the drug in the body are examined.
🔬 Security Tests on Target Animal Types: The possible side effects of the drug in the target animal species are evaluated.
🔬 Environmental Impact Assessments: The potential negative effects of the drug on the environment are being investigated.
Performing all these tests in accordance with GLP standards increases the reliability and legal acceptance of the data obtained.
Why are in vivo tests required?
In contrast to human medicines, veterinary medicines have effects on food safety, environmental health and zoonotic diseases in addition to animal health.
- Preventing unexpected side effects in animals
- Preventing serious problems such as antibiotic resistance
- Safety of animal products such as meat, milk and eggs
- Determination of possible negative effects on the environment
- Compliance with legal regulations in the phases of approval and market launch
GLP standards for safe veterinary medicines
In-vivo tests within the framework of the GLP are a scientific and legal obligation that indirectly serves human health. Reliable data obtained with GLP-compliant tests is the most important proof of the effectiveness and safety of products.
If you would like to have reliable in-vivo tests carried out as part of the registration procedures for your veterinary medicines, you can rely on our competent laboratory services.