Plant Protection Products (PPP)
Pesticides undergo rigorous physicochemical and toxicological evaluations regarding safety, efficacy, and regulatory approval.
Physico-chemical Tests – Plant Protection Products (PPP)
International procedures are applied to ensure that there are no compromises in the quality and safety of plant protection products. This involves the use of standardized test protocols developed by organizations such as CIPAC and OECD. These tests incorporate sophisticated analytical techniques such as HPLC (High-Performance Liquid Chromatography) and GC (Gas Chromatography) for the precise identification and quantification of active ingredients.
- CIPAC MT 3.3 – Density
- CIPAC MT 75 – pH Determination
- CIPAC MT 53.3 – Wettability
- CIPAC MT 184 – Suspensibility of Aqueous Suspension Concentrates
- CIPAC MT 36 – Emulsion Stability
- CIPAC MT 185.1 – Wet Sieve Test
- CIPAC MT 171.1 – Dustiness
- CIPAC MT 172.2 – Flowability
The OECD Test Guidelines applied within the framework of international chemical safety standards are:
- OECD TG 101 – UV/Visible Spectrum Analysis
- OECD TG 104 – Vapour Pressure Measurement
- OECD TG 105 – Water Solubility
- OECD TG 107 – Partition Coefficient (n-Octanol/Water)
Furthermore, the CIPAC MT 46.3 method for accelerated storage is applied to test the chemical and physical stability of the product under accelerated conditions.
In-vivo Tests – Safety Assessment of Plant Protection Products
To ensure that plant protection products are safe for human health and the environment, the following OECD tests are employed. These tests assess the acute toxicity and irritation potential of the products and are also known as "Six-Pack Tests":
- OECD TG 420/423 – Acute Oral Toxicity
- OECD TG 402 – Acute Dermal Toxicity
- OECD TG 403 – Acute Inhalation Toxicity
- OECD TG 404 – Acute Skin Irritation and Corrosion
- OECD TG 405 – Acute Eye Irritation and Corrosion
- OECD TG 406 – Skin Sensitization

