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GLP Studies – CIPAC MT 3.3 – Determination of Density

What is CIPAC?

CIPAC (Collaborative International Pesticides Analytical Council) is an international organization responsible for the development and standardization of analytical methods for pesticides and biocide products. The methods published by CIPAC are globally recognized and are used as a reference in registration procedures.

CIPAC MT 3.3 – What is a Density Test?

CIPAC MT 3.3 is a standard analytical method for determining the density (d= m/v) of pesticide and biocide formulations. Density is a crucial parameter for evaluating the physical properties, formulation quality, and homogeneity of a product.

Product density is important for correct labeling, accurate dosage calculation, and adherence to quality standards.

Why is a Density Test Performed under GLP?

Thanks to density tests conducted under Good Laboratory Practice (GLP):

  • Valid data for product registration applications are submitted.
  • Compliance with national and international regulations
  • Transparency in control processes
  • Consistency between product batches

CIPAC MT 3.3 How is the Density Test Performed?

Density determination is carried out according to CIPAC methods using a pycnometer, a hydrometer, or a densimeter.

Basic Analytical Steps:

  1. The pycnometer or densimeter is calibrated.
  2. The product is prepared for measurement at an appropriate temperature (typically 20 °C or 25 °C).
  3. The pycnometer is weighed first empty and then with the product.
  4. Density is calculated from the mass and volume values.
  5. The result is evaluated in accordance with the CIPAC MT 3.3 method.

For which products is it mandated?

The density determination according to CIPAC MT 3.3 is specifically performed for the following product groups:

  • Biocidal Products
  • Pesticide formulations
  • Plant protection products
  • Industrial chemicals
  • Active Pharmaceutical Ingredients (depending on the formulation)

Where are the results of the density determination used?

  • Registration dossiers
  • Safety Data Sheets (SDS/MSDS)
  • Technical product specifications
  • Determination of transport and storage conditions
  • Quality control of production batches

Nanolab GLP-compliant CIPAC density measurement service

Nanolab performs density analyses in full compliance with CIPAC methods and GLP standards.

Discover all our services within the framework of GLP.

Nanolab continues to offer reliable and transparent analytical procedures. Contact us.

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