{"id":4108,"date":"2026-03-01T18:22:22","date_gmt":"2026-03-01T18:22:22","guid":{"rendered":"https:\/\/nano-test.de\/?p=4108"},"modified":"2026-03-12T18:59:11","modified_gmt":"2026-03-12T18:59:11","slug":"chlorhexidindigluconat-bestimmung-cipac-36-und-ijpsr","status":"publish","type":"post","link":"https:\/\/nano-test.de\/it\/2026\/03\/01\/chlorhexidindigluconat-bestimmung-cipac-36-und-ijpsr\/","title":{"rendered":"Determinazione della clorexidina digluconato: CIPAC 36 e IJPSR"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4108\" class=\"elementor elementor-4108\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6882b921 ts-col-stretched-none ts-bg-color-over-image elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6882b921\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-44fdcf1d ts-bg-color-over-image\" data-id=\"44fdcf1d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7d4336e6 elementor-widget elementor-widget-text-editor\" data-id=\"7d4336e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2><span style=\"color: #000000;\"><strong>CIPAC 36 Determinazione della clorexidina digluconato: approccio analitico e significato<\/strong><\/span><\/h2><p><span style=\"color: #000000;\">Chlorhexidindigluconat (CHX) ist ein <a href=\"https:\/\/nano-test.de\/it\/service\/biozid\/\">Biocida<\/a>, das aufgrund seiner starken antimikrobiellen und antiseptischen Eigenschaften sowohl in medizinischen als auch in Hygieneprodukten weit verbreitet ist. Aufgrund seiner Wirksamkeit insbesondere gegen grampositive und gramnegative Bakterien wird dieser Wirkstoff in Desinfektionsl\u00f6sungen, chirurgischen Antiseptika und Mundpflegeprodukten verwendet. Die <i>korrekte Bestimmung der Wirkstoffmenge<\/i> in solchen Produkten ist jedoch f\u00fcr die Wirksamkeit und Sicherheit von entscheidender Bedeutung.<\/span><\/p><h3><span style=\"color: #000000;\"><strong>Determinazione della clorexidina diluconato: perch\u00e9 \u00e8 importante?<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">Die Wirksamkeit eines bioziden Produkts h\u00e4ngt von der richtigen Konzentration des Wirkstoffs ab. Zu niedrige Dosierungen machen das Produkt unwirksam, w\u00e4hrend zu hohe Dosierungen die menschliche Gesundheit sch\u00e4digen k\u00f6nnen. Aus diesem Grund wird im Rahmen der Produktqualit\u00e4tskontrolle eine <i>Bestimmung von Chlorhexidindigluconat<\/i> durchgef\u00fchrt. Diese Analyse:<\/span><\/p><ul><li><span style=\"color: #000000;\">conferma il contenuto di sostanza attiva del prodotto,<\/span><\/li><li><span style=\"color: #000000;\">assicura il rispetto di normative e norme e<\/span><\/li><li><span style=\"color: #000000;\">Garantisce l'efficacia e la sicurezza del prodotto.<\/span><\/li><\/ul><h3><span style=\"color: #000000;\"><strong>Metodo IJSPR (2015): Determinazione della clorexidina digluconato mediante HPLC<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">Die 2015 im <i>International Journal of Pharmaceutical Sciences and Research (<a href=\"https:\/\/ijpsr.com\/\">IJPSR<\/a>), Band 6, Ausgabe 12<\/i> ver\u00f6ffentlichte Methodik beschreibt eine analytische Bestimmungsmethode auf Basis der <i>Cromatografia liquida pesante (HPLC)<\/i>. Diese Methode wurde entwickelt, um den Chlorhexidin-Gehalt in CHX-haltigen bioziden L\u00f6sungen oder Produkten mit hoher Genauigkeit zu bestimmen.<\/span><\/p><p><span style=\"color: #000000;\"><strong>Principio di analisi e propriet\u00e0 di base:<\/strong><\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f Verwendung eines <i>HPLC-UV\/DAD<\/i>-Detektorsystems<\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f Gli standard CHX sono prodotti in un intervallo di concentrazione specifico<\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f Il contenuto viene misurato quantitativamente con curve di calibrazione lineare<\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f I campioni disciolti vengono separati con una fase mobile adatta<\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f Rilevamento UV ad una lunghezza d'onda di 254 nm<\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f I dati vengono valutati durante l'analisi utilizzando il software (es. Empower)<\/span><\/p><p><span style=\"color: #000000;\">Diese Art von chromatographischen Methoden gew\u00e4hrleistet <i>hohe Genauigkeit, Wiederholbarkeit und Pr\u00e4zision<\/i> und wird daher in Qualit\u00e4tskontrolllabors f\u00fcr Routineanalysen bevorzugt.<\/span><\/p><h3><span style=\"color: #000000;\"><strong>Aree di applicazione dei metodi di analisi CHX<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">Questo tipo di metodo di determinazione non solo viene utilizzato teoricamente in laboratorio, ma utilizzato anche quotidianamente nel controllo di qualit\u00e0 dei prodotti reali. In particolare:<\/span><\/p><ul><li><span style=\"color: #000000;\">Rilevamento di principi attivi in soluzioni biocidiche<\/span><\/li><li><span style=\"color: #000000;\">Ispezione di qualit\u00e0 dopo la produzione di disinfettanti<\/span><\/li><li><span style=\"color: #000000;\">Processi di controllo da parte dei produttori e delle autorit\u00e0 di vigilanza<\/span><\/li><li><span style=\"color: #000000;\">Applicazione come metodo di riferimento nei laboratori accreditati<\/span><\/li><\/ul><h3><span style=\"color: #000000;\"><strong>Precisione analitica per qualit\u00e0 e sicurezza<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">Chlorhexidindigluconat ist ein starkes Antiseptikum, jedoch ist die Anwendung <i>standardisierter Analysemethoden<\/i> erforderlich, um diese Wirksamkeit in Produkten korrekt nachzuweisen. Die IJPSR-2015-Methodik erm\u00f6glicht die schnelle und zuverl\u00e4ssige Messung von CHX in bioziden Produkten mittels <b>HPLC-basierter SHG-Bestimmung<\/b>.<\/span><\/p><p><span style=\"color: #000000;\">Tali analisi sono importanti sia per la compliance che per la salute umana.<\/span><\/p><p><span style=\"color: #000000;\">Contattaci! info@nano-test.de<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>CIPAC 36 Chlorhexidindigluconat-Bestimmung: Analytischer Ansatz und Bedeutung Chlorhexidindigluconat (CHX) ist ein Biozid, das aufgrund seiner starken antimikrobiellen und antiseptischen Eigenschaften sowohl in medizinischen als auch in Hygieneprodukten weit verbreitet ist. Aufgrund seiner Wirksamkeit insbesondere gegen grampositive und gramnegative Bakterien wird dieser Wirkstoff in Desinfektionsl\u00f6sungen, chirurgischen Antiseptika und Mundpflegeprodukten verwendet. Die korrekte Bestimmung der Wirkstoffmenge in \u2026 <a href=\"https:\/\/nano-test.de\/it\/2026\/03\/01\/chlorhexidindigluconat-bestimmung-cipac-36-und-ijpsr\/\" class=\"more-link\" title=\"Continue reading &lt;span class=\" screen-reader-text>Chlorhexidindigluconat-Bestimmung: CIPAC 36 und IJPSR\u201c&gt;Continue reading <span class=\"screen-reader-text\">Determinazione della clorexidina digluconato: CIPAC 36 e IJPSR<\/span><\/a><\/p>\n","protected":false},"author":4,"featured_media":4109,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-4108","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biozid-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Chlorhexidindigluconat-Bestimmung: CIPAC 36 und IJPSR | Nano-Test\u00ae<\/title>\n<meta name=\"description\" content=\"Pr\u00e4zise Bestimmung von Chlorhexidindigluconat mit HPLC gem\u00e4\u00df CIPAC 36 &amp; IJPSR 2015. 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