{"id":4431,"date":"2026-08-20T07:08:02","date_gmt":"2026-08-20T07:08:02","guid":{"rendered":"https:\/\/nano-test.de\/?p=4431"},"modified":"2026-08-20T07:25:49","modified_gmt":"2026-08-20T07:25:49","slug":"primary-aromatic-amine-paa-analyses-ppwr-and-10-2011-eu","status":"publish","type":"post","link":"https:\/\/nano-test.de\/fr\/2026\/08\/20\/primary-aromatic-amine-paa-analyses-ppwr-and-10-2011-eu\/","title":{"rendered":"Analyses des amines aromatiques primaires (PAA) | PPWR"},"content":{"rendered":"\t\t
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Introduction : La signification r\u00e9glementaire et les risques pour la sant\u00e9 des amines aromatiques primaires<\/span><\/h2>\nPrim\u00e4re aromatische Amine (PAA) sind organische Verbindungen, deren chemische Struktur eine prim\u00e4re Aminogruppe (-NH\u2082) enth\u00e4lt, die direkt an einen oder mehrere aromatische Ringe gebunden ist. Diese Stoffgruppe ist f\u00fcr die Sicherheit von Verpackungsmaterialien, die mit Lebensmitteln in Kontakt kommen, von besonderer regulatorischer Bedeutung. PAAs k\u00f6nnen durch den Abbau von Azofarbstoffen entstehen, die bei der Verpackungsherstellung verwendet werden, oder aus unvollst\u00e4ndigen Aush\u00e4rtungsreaktionen von Klebstoffen auf Polyurethanbasis stammen. Die Europ\u00e4ische Beh\u00f6rde f\u00fcr Lebensmittelsicherheit (EFSA)<\/a> und die Internationale Agentur f\u00fcr Krebsforschung (IARC)<\/a> haben viele PAA-Verbindungen als genotoxische Karzinogene eingestuft. Aus diesem Grund begrenzt die Verordnung (EU) Nr. 10\/2011 der Europ\u00e4ischen Union \u00fcber Kunststoffmaterialien die Migration von PAA aus Kunststoffmaterialien, die mit Lebensmitteln in Kontakt kommen, streng auf ein extrem niedriges Niveau. Mit der Einf\u00fchrung der PPWR wurde diese Kontrolle weiter versch\u00e4rft; PAA-Analysen sind zu einem unverzichtbaren Bestandteil der Konformit\u00e4tsbewertungen f\u00fcr Verpackungshersteller geworden. Nano-Test Laboratory Services f\u00fchrt PAA-Analysen unter Verwendung validierter LC-MS\/MS-Methoden durch, die den GLP-Grunds\u00e4tzen vollst\u00e4ndig entsprechen; wir bieten unseren Kunden Bewertungen der Einhaltung gesetzlicher Vorschriften sowie umfassende technische Beratung.<\/span>\n

Structure chimique, sources et cadre juridique des PAA<\/span><\/h2>\nLes amines aromatiques primaires ne constituent pas un compos\u00e9 chimique unique, mais une large famille de substances partageant une caract\u00e9ristique structurelle commune. Au sein de cette famille, certains compos\u00e9s ont \u00e9t\u00e9 identifi\u00e9s dont les noms sont explicitement inscrits dans le R\u00e8glement (UE) n\u00b0 10\/2011 et dont la migration est interdite.<\/span>\n

Principales sources de PAA dans les mat\u00e9riaux d\u2019emballage<\/span><\/h3>\nLe tableau suivant r\u00e9sume les raisons de l\u2019apparition des APA dans les mat\u00e9riaux d\u2019emballage, leurs m\u00e9canismes de formation et les types d\u2019emballages dans lesquels ces m\u00e9canismes sont g\u00e9n\u00e9ralement observ\u00e9s :<\/span>\n\n\n\n\n\n\n\n\n
M\u00e9canisme de formation<\/span><\/th>\nProcessus de cr\u00e9ation<\/span><\/th>\nType d\u2019emballage \/ application typique<\/span><\/th>\nExplication<\/span><\/th>\n<\/tr>\n<\/thead>\n
D\u00e9gradation des colorants azo<\/strong><\/span><\/td>\nS\u00e9paration de la double liaison azote-azote (N=N)<\/span><\/td>\nFilms plastiques imprim\u00e9s, emballages color\u00e9s, emballages en papier\/carton<\/span><\/td>\nDans des conditions r\u00e9ductrices (par exemple dans l\u2019environnement acide ou r\u00e9ducteur des aliments), les colorants azo peuvent lib\u00e9rer des PAA en rompant la liaison azotique dans sa structure.<\/span><\/td>\n<\/tr>\n
Durcissement incomplet des adh\u00e9sifs en polyur\u00e9thane<\/strong><\/span><\/td>\nConversion des isocyanates aromatiques en PAA lors de la r\u00e9action avec l\u2019eau<\/span><\/td>\nEmballage en stratifi\u00e9 multicouche, films flexibles,<\/span>\nPochette<\/span><\/td>\nSi les adh\u00e9sifs polyur\u00e9thanes \u00e0 base d\u2019isocyanates aromatiques ne sont pas compl\u00e8tement durcis, ils peuvent subir une hydrolyse lorsqu\u2019ils entrent en contact avec l\u2019eau, formant des PAA (par exemple MDA \u2013 m\u00e9thyl\u00e9nedianiline).<\/span><\/td>\n<\/tr>\n
Impuret\u00e9s dans les mati\u00e8res premi\u00e8res<\/strong><\/span><\/td>\nR\u00e9sidus de PAA produits lors du processus de fabrication de monom\u00e8res ou d\u2019additifs<\/span><\/td>\nMati\u00e8res premi\u00e8res polym\u00e8res, masterbatchs, additifs techniques<\/span><\/td>\nCertains produits chimiques d\u2019ing\u00e9nierie peuvent contenir de petites quantit\u00e9s d\u2019impuret\u00e9s de PAA provenant des proc\u00e9d\u00e9s de production.<\/span><\/td>\n<\/tr>\n
Encres et rev\u00eatements d\u2019impression<\/strong><\/span><\/td>\nD\u00e9gradation des pigments et liants utilis\u00e9s dans les formulations d\u2019encre<\/span><\/td>\nEmballages imprim\u00e9s ext\u00e9rieurement, \u00e9tiquettes, carton enduit<\/span><\/td>\nEn particulier, la migration de la d\u00e9coloration (transfert de l\u2019empreinte \u00e0 la surface de l\u2019emballage en contact avec la nourriture) peut entra\u00eener une contamination par la PAA.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Compos\u00e9s importants de la PAA soumis \u00e0 la r\u00e9glementation<\/span><\/h3>\nLe R\u00e8glement (UE) n\u00b0 10\/2011 \u00e9num\u00e8re certains compos\u00e9s de la PAA pour lesquels la migration \u00e0 partir de mat\u00e9riaux plastiques entrant en contact avec la nourriture ne doit pas \u00eatre d\u00e9tectable (valeur limite : 0,01 mg\/kg d\u2019aliments ou simulans). Le tableau suivant pr\u00e9sente les principaux compos\u00e9s PAA de cette liste, ainsi que leurs num\u00e9ros CAS et leurs sources typiques :<\/span>\n\n\n\n\n\n\n\n\n\n\n\n\n
Amine aromatique primaire<\/span><\/th>\nAbr\u00e9viation \/ num\u00e9ro de CAS<\/span><\/th>\nClassification toxicologique<\/span><\/th>\nSource typique \/ teinture Azo apparent\u00e9e<\/span><\/th>\n<\/tr>\n<\/thead>\n
4,4\u2032-m\u00e9thyl\u00e9nedianiline<\/strong><\/span><\/td>\nMDA\/101-77-9<\/span><\/td>\ncanc\u00e9rog\u00e8ne (Groupe 2B de l\u2019IARC) ; Mutag\u00e8ne<\/span><\/td>\ndes adh\u00e9sifs en polyur\u00e9thane ; Hydrolyse isocyanate<\/span><\/td>\n<\/tr>\n
Benzidine<\/strong><\/span><\/td>\nBZD \/ 92-87-5<\/span><\/td>\ncanc\u00e9rog\u00e8ne (Groupe 1 de l\u2019IARC) ; G\u00e9notoxique<\/span><\/td>\ndes colorants azo (\u00e0 base de benzidine) ; Pigments interdits<\/span><\/td>\n<\/tr>\n
2-Naphthylamin<\/strong><\/span><\/td>\n2-NA \/ 91-59-8<\/span><\/td>\ncanc\u00e9rog\u00e8ne (Groupe 1 de l\u2019IARC) ; G\u00e9notoxique<\/span><\/td>\ncolorants azo (\u00e0 base de 2-naphthylamine) ; Pigments interdits<\/span><\/td>\n<\/tr>\n
4-Aminobiphenyl<\/strong><\/span><\/td>\n4-ABP \/ 92-67-1<\/span><\/td>\ncanc\u00e9rog\u00e8ne (Groupe 1 de l\u2019IARC) ;<\/span>\nG\u00e9notoxique<\/span><\/td>\ndes colorants azo (\u00e0 base de 4-aminoobiph\u00e9nyl) ; Pigments interdits<\/span><\/td>\n<\/tr>\n
O-toluidine<\/strong><\/span><\/td>\n2-M\u00e9thylaniline\/95-53-4<\/span><\/td>\ncanc\u00e9rog\u00e8ne (Groupe 1 de l\u2019IARC) ; G\u00e9notoxique<\/span><\/td>\nteintures azo ; Encres d\u2019impression<\/span><\/td>\n<\/tr>\n
4-Chloranilin<\/strong><\/span><\/td>\n4-CA \/ 106-47-8<\/span><\/td>\nsuspicion de canc\u00e9rog\u00e9nicit\u00e9 ; Mutag\u00e8ne<\/span><\/td>\nteintures azo ; Impuret\u00e9s pigmentaires<\/span><\/td>\n<\/tr>\n
Aniline<\/strong><\/span><\/td>\nANL \/ 62-53-3<\/span><\/td>\ncanc\u00e9rog\u00e8ne (Groupe 2A de l\u2019IARC) ; toxique<\/span><\/td>\nteintures azo ; une vari\u00e9t\u00e9 de pigments et d\u2019additifs<\/span><\/td>\n<\/tr>\n
2,4-Iamine de tolu\u00e8ne<\/strong><\/span><\/td>\n2,4-TDA \/ 95-80-7<\/span><\/td>\nsuspicion de canc\u00e9rog\u00e9nicit\u00e9 ; Mutag\u00e8ne<\/span><\/td>\ndes adh\u00e9sifs en polyur\u00e9thane ; Hydrolyse isocyanate<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\nNote : Le R\u00e8glement (UE) n\u00b0 10\/2011 d\u00e9finit la limite totale de migration des PAA comme \u00ab ind\u00e9tectable \u00bb et la limite de d\u00e9tection analytique est fix\u00e9e \u00e0 0,01 mg\/kg (par aliment ou simulant). Cette limite s\u2019applique \u00e0 la somme de tous les compos\u00e9s PAA list\u00e9s. Nano-Test peut d\u00e9terminer simultan\u00e9ment plus de 20 compos\u00e9s PAA en \u00e9largissant la port\u00e9e de l\u2019analyse selon les besoins des clients.<\/em><\/span>\n

M\u00e9thodologie d\u2019analyse PAA au laboratoire de nano-essais<\/span><\/h2>\nL\u2019analyse des amines aromatiques primaires est une proc\u00e9dure analytique n\u00e9cessitant une grande sensibilit\u00e9 et s\u00e9lectivit\u00e9 en raison des faibles limites de migration de ces compos\u00e9s (0,01 mg\/kg). Dans le laboratoire de nano-test, les analyses PAA sont r\u00e9alis\u00e9es en utilisant des m\u00e9thodes LC-MS\/MS qui ont \u00e9t\u00e9 optimis\u00e9es et enti\u00e8rement valid\u00e9es pour ces besoins.<\/span>\n

Flux de travail analytique : des tests de migration \u00e0 la d\u00e9termination quantitative<\/span><\/h3>\nLe tableau suivant d\u00e9crit l\u2019ensemble du flux de travail pour l\u2019analyse PAA dans le laboratoire de Nano Test :<\/span>\n\n\n\n\n\n\n\n\n\n
Pas<\/span><\/th>\nApproche<\/span><\/th>\nD\u00e9tails techniques<\/span><\/th>\n<\/tr>\n<\/thead>\n
1. Conception des exp\u00e9riences<\/strong><\/span><\/td>\nD\u00e9termination des simulants et conditions de test<\/span><\/td>\nUn simulant alimentaire appropri\u00e9 doit \u00eatre s\u00e9lectionn\u00e9 conform\u00e9ment aux annexes III et V du R\u00e8glement (UE) n\u00b0 10\/2011. Le simulant le plus couramment utilis\u00e9 pour l\u2019analyse PAA est le simulant B (acide ac\u00e9tique \u00e0 3 %), qui repr\u00e9sente les aliments acides et simule le mieux le risque de r\u00e9duction du colorant azo. Les Simulans A (10 % d\u2019\u00e9thanol) et Simulans C (20 % d\u2019\u00e9thanol) peuvent \u00e9galement \u00eatre utilis\u00e9s.<\/span><\/td>\n<\/tr>\n
2. Revue de la migration<\/strong><\/span><\/td>\nContact contr\u00f4l\u00e9<\/span><\/td>\nL\u2019\u00e9chantillon du paquet est mis en contact avec le simulant s\u00e9lectionn\u00e9 \u00e0 l\u2019aide de cellules de contact standard ou par la m\u00e9thode d\u2019immersion \u00e0 la temp\u00e9rature et \u00e0 la dur\u00e9e sp\u00e9cifi\u00e9es. Les conditions de test sont choisies de mani\u00e8re \u00e0 refl\u00e9ter le sc\u00e9nario d\u2019application le plus d\u00e9favorable.<\/span><\/td>\n<\/tr>\n
3. Pr\u00e9paration de l\u2019\u00e9chantillon<\/strong><\/span><\/td>\nExtraction et purification<\/span><\/td>\nApr\u00e8s un ajustement appropri\u00e9 du pH, l\u2019extrait de simulans est purifi\u00e9 par extraction en phase solide (SPE) ou par extraction liquide-liquide. Un antioxydant est ajout\u00e9 pour assurer la stabilit\u00e9 des compos\u00e9s PAA. Les effets matriciels sont corrig\u00e9s en ajoutant des \u00e9talons internes marqu\u00e9s par des isotopes (par exemple, aniline-d5, MDA-d4).<\/span><\/td>\n<\/tr>\n
4. Analyse LC-MS\/MS<\/strong><\/span><\/td>\nD\u00e9termination quantitative<\/span><\/td>\nApr\u00e8s s\u00e9paration sur une colonne de LC \u00e0 phase invers\u00e9e, l\u2019extrait purifi\u00e9 est analys\u00e9 par ionisation ESI dans un spectrom\u00e8tre de masse triple quadrupole. Pour chaque connexion PAA, deux transitions MRM sont surveill\u00e9es. La valeur de la LOQ a \u00e9t\u00e9 valid\u00e9e \u00e0 \u2264 0,005 mg\/kg afin de fournir une \u00e9valuation fiable de la limite de SML de 0,01 mg\/kg. <\/span><\/td>\n<\/tr>\n
5. \u00c9valuation et rapport<\/strong><\/span><\/td>\nComparaison avec la SML et la D\u00e9claration de conformit\u00e9<\/span><\/td>\nLes r\u00e9sultats quantitatifs obtenus sont compar\u00e9s \u00e0 la limite totale de la PAA de 0,01 mg\/kg. Pour les compos\u00e9s non d\u00e9tect\u00e9s, le r\u00e9sultat est indiqu\u00e9 comme \u00ab < LOQ \u00bb. Un rapport d\u2019analyse complet conforme aux BPL est r\u00e9dig\u00e9.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Param\u00e8tres de contr\u00f4le qualit\u00e9 et de validation de la m\u00e9thode<\/span><\/h3>\nLe tableau suivant r\u00e9sume les param\u00e8tres de contr\u00f4le qualit\u00e9 et les crit\u00e8res d\u2019acceptation les plus importants utilis\u00e9s pour les analyses PAA dans le laboratoire de nano-test :<\/span>\n\n\n\n\n\n\n\n\n\n\n\n
Param\u00e8tres de contr\u00f4le de la qualit\u00e9<\/span><\/th>\nFr\u00e9quence d'application<\/span><\/th>\nCrit\u00e8res d\u2019acceptation<\/span><\/th>\n<\/tr>\n<\/thead>\n
Test de proc\u00e9d\u00e9 \u00e0 blanc<\/strong><\/span><\/td>\nMinimum 1 par ex\u00e9cution d\u2019analyse<\/span><\/td>\nToutes les connexions PAA de destination < LOQ<\/span><\/td>\n<\/tr>\n
Taux de r\u00e9cup\u00e9ration sur l\u2019addition de matrice<\/strong><\/span><\/td>\nPar ex\u00e9cution pour chaque type de simulant<\/span><\/td>\nTaux de r\u00e9cup\u00e9ration de 80 % \u00e0 120 %<\/span><\/td>\n<\/tr>\n
Taux de r\u00e9cup\u00e9ration de l\u2019\u00e9talon interne<\/strong><\/span><\/td>\nAjout\u00e9 \u00e0 chaque \u00e9chantillon<\/span><\/td>\n60 % \u2013 140 % de r\u00e9cup\u00e9ration<\/span><\/td>\n<\/tr>\n
Standard de contr\u00f4le (Solution PAA mixte)<\/strong><\/span><\/td>\nMinimum 1 par ex\u00e9cution d\u2019analyse<\/span><\/td>\nDans \u00b120 % de la concentration attendue<\/span><\/td>\n<\/tr>\n
Double analyse<\/strong><\/span><\/td>\n1 pour 10 \u00e9chantillons<\/span><\/td>\n\u00c9cart de pourcentage relatif (DPR) \u2264 20 %<\/span><\/td>\n<\/tr>\n
Pr\u00e9cision (r\u00e9cup\u00e9ration)<\/strong><\/span><\/td>\n\u00c0 3 niveaux de concentration diff\u00e9rents pendant la validation<\/span><\/td>\nEntre 80 % et 120 %<\/span><\/td>\n<\/tr>\n
Limite de quantification (LOQ)<\/strong><\/span><\/td>\nD\u00e9termin\u00e9 lors de la validation<\/span><\/td>\n\u2264 0,005 mg\/kg (limite SML inf\u00e9rieure \u00e0 0,01 mg\/kg)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Mod\u00e8le de service int\u00e9gr\u00e9 de Nano-Test pour l\u2019analyse PAA<\/span><\/h2>\nEn tant que Nano-Test Laboratory Services, nous ne proposons pas les analyses PAA comme des tests individuels, mais comme une partie int\u00e9gr\u00e9e du processus de conformit\u00e9 selon PPWR et 10\/2011\/EU. Notre mod\u00e8le de service se compose des composants r\u00e9sum\u00e9s dans le tableau suivant :<\/span>\n\n\n\n\n\n\n\n\n\n
Chronique des services<\/span><\/th>\nPort\u00e9e<\/span><\/th>\nAvantages pour le client<\/span><\/th>\n<\/tr>\n<\/thead>\n
Conseils sur les exigences r\u00e9glementaires<\/strong><\/span><\/td>\nD\u00e9termination des compos\u00e9s PAA \u00e0 analyser sur la base de la composition du produit ainsi que des adh\u00e9sifs et encres d\u2019impression utilis\u00e9s ; S\u00e9lection des simulants appropri\u00e9s et conditions de test<\/span><\/td>\nOptimisation des co\u00fbts gr\u00e2ce \u00e0 la bonne strat\u00e9gie de test ; \u00e9viter les analyses incompl\u00e8tes ou inutiles<\/span><\/td>\n<\/tr>\n
Services d\u2019essais analytiques<\/strong><\/span><\/td>\nM\u00e9thode LC-MS\/MS valid\u00e9e conforme \u00e0 la GLP pour la d\u00e9termination quantitative simultan\u00e9e de plus de 20 compos\u00e9s PAA<\/span><\/td>\nDes donn\u00e9es d'analyse accept\u00e9es par les autorit\u00e9s de r\u00e9glementation, fond\u00e9es et tra\u00e7ables<\/span><\/td>\n<\/tr>\n
\u00c9valuation de la conformit\u00e9<\/strong><\/span><\/td>\n\u00c9mission d'une d\u00e9claration de conformit\u00e9\/non-conformit\u00e9 par comparaison des r\u00e9sultats avec la valeur limite SML de 0,01 mg\/kg de PAA total, ce qui conduit \u00e0 une d\u00e9claration de conformit\u00e9 ou de non-conformit\u00e9<\/span><\/td>\nUne \u00e9valuation claire et contraignante du statut juridique du produit<\/span><\/td>\n<\/tr>\n
Support de la documentation technique<\/strong><\/span><\/td>\nFourniture d'un rapport d'analyse complet et d'une d\u00e9claration de conformit\u00e9 (DoC)<\/span><\/td>\nAssistance au client dans la pr\u00e9paration compl\u00e8te et correcte de sa propre d\u00e9claration de conformit\u00e9<\/span><\/td>\n<\/tr>\n
Conseils sur la non-conformit\u00e9<\/strong><\/span><\/td>\nD\u00e9termination de la cause du probl\u00e8me en cas de d\u00e9passement de la valeur limite (adh\u00e9sif, encre d'impression, pigment ou mati\u00e8re premi\u00e8re) et recommandations pour les mesures correctives<\/span><\/td>\n\u00c9limination permanente du probl\u00e8me et \u00e9vitement des non-conformit\u00e9s r\u00e9currentes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\nPolyurethan-Klebstoffe, die in mehrschichtigen Laminatverpackungen verwendet werden, und Azofarbstoffe, die in bedruckten Verpackungen zum Einsatz kommen, sind die h\u00e4ufigsten Ursachen f\u00fcr PAA-Migration<\/a>. Bei Nano-Test liefern wir mehr als nur Analysedaten; wir bieten unseren Kunden auch technische Beratung zur Ursachenanalyse potenzieller Quellen f\u00fcr festgestellte PAA-Kontaminationen, zur Optimierung der Klebstoffaush\u00e4rtung und zur Auswahl alternativer Rohstoffe.<\/span>\n\nPour vous assurer que vos emballages destin\u00e9s au march\u00e9 europ\u00e9en respectent les r\u00e9glementations PAA conform\u00e9ment au PPWR et au 10\/2011\/UE, et pour effectuer vos analyses avec un partenaire fiable et exp\u00e9riment\u00e9, veuillez contacter notre \u00e9quipe d'experts pour obtenir des informations d\u00e9taill\u00e9es sur les services de laboratoire accr\u00e9dit\u00e9s et le conseil technique de Nano-Test.<\/span>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Einleitung: Die regulatorische Bedeutung und die Gesundheitsrisiken prim\u00e4rer aromatischer Amine Prim\u00e4re aromatische Amine (PAA) sind organische Verbindungen, deren chemische Struktur eine prim\u00e4re Aminogruppe (-NH\u2082) enth\u00e4lt, die direkt an einen oder mehrere aromatische Ringe gebunden ist. Diese Stoffgruppe ist f\u00fcr die Sicherheit von Verpackungsmaterialien, die mit Lebensmitteln in Kontakt kommen, von besonderer regulatorischer Bedeutung. PAAs k\u00f6nnen \u2026 Analysen von prim\u00e4ren aromatischen Aminen (PAA) | PPWR\u00ab\u00a0>Continue reading Analyses des amines aromatiques primaires (PAA) | PPWR<\/span><\/a><\/p>\n","protected":false},"author":4,"featured_media":4432,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[42],"tags":[],"class_list":["post-4431","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-verpackung-blog"],"yoast_head":"\nAnalysen von prim\u00e4ren aromatischen Aminen (PAA) | PPWR | Nano-Test\u00ae<\/title>\n<meta name=\"description\" content=\"Wir f\u00fchren Analysen auf prim\u00e4re aromatische Amine (PAA) f\u00fcr Ihre Lebensmittelverpackungen gem\u00e4\u00df der PPWR und der Verordnung (EU) Nr. 10\/2011 durch; wir bescheinigen Ihnen die vollst\u00e4ndige Einhaltung des SML-Grenzwerts von 0,01 mg\/kg.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nano-test.de\/2026\/08\/20\/primary-aromatic-amine-paa-analyses-ppwr-and-10-2011-eu\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Analysen von prim\u00e4ren aromatischen Aminen (PAA) | PPWR | Nano-Test\u00ae\" \/>\n<meta property=\"og:description\" content=\"Wir f\u00fchren Analysen auf prim\u00e4re aromatische Amine (PAA) f\u00fcr Ihre Lebensmittelverpackungen gem\u00e4\u00df der PPWR und der Verordnung (EU) Nr. 10\/2011 durch; 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