{"id":4108,"date":"2026-03-01T18:22:22","date_gmt":"2026-03-01T18:22:22","guid":{"rendered":"https:\/\/nano-test.de\/?p=4108"},"modified":"2026-03-12T18:59:11","modified_gmt":"2026-03-12T18:59:11","slug":"chlorhexidindigluconat-bestimmung-cipac-36-und-ijpsr","status":"publish","type":"post","link":"https:\/\/nano-test.de\/en\/2026\/03\/01\/chlorhexidindigluconat-bestimmung-cipac-36-und-ijpsr\/","title":{"rendered":"Chlorhexidine digluconate determination: CIPAC 36 and IJPSR"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4108\" class=\"elementor elementor-4108\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6882b921 ts-col-stretched-none ts-bg-color-over-image elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6882b921\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-44fdcf1d ts-bg-color-over-image\" data-id=\"44fdcf1d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7d4336e6 elementor-widget elementor-widget-text-editor\" data-id=\"7d4336e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2><span style=\"color: #000000;\"><strong>CIPAC 36 Chlorhexidine digluconate determination: Analytical approach and significance<\/strong><\/span><\/h2><p><span style=\"color: #000000;\">Chlorhexidindigluconat (CHX) ist ein <a href=\"https:\/\/nano-test.de\/en\/service\/biozid\/\">Biocide<\/a>, das aufgrund seiner starken antimikrobiellen und antiseptischen Eigenschaften sowohl in medizinischen als auch in Hygieneprodukten weit verbreitet ist. Aufgrund seiner Wirksamkeit insbesondere gegen grampositive und gramnegative Bakterien wird dieser Wirkstoff in Desinfektionsl\u00f6sungen, chirurgischen Antiseptika und Mundpflegeprodukten verwendet. Die <i>korrekte Bestimmung der Wirkstoffmenge<\/i> in solchen Produkten ist jedoch f\u00fcr die Wirksamkeit und Sicherheit von entscheidender Bedeutung.<\/span><\/p><h3><span style=\"color: #000000;\"><strong>Determination of chlorhexidine digluconate: Why is this important?<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">Die Wirksamkeit eines bioziden Produkts h\u00e4ngt von der richtigen Konzentration des Wirkstoffs ab. Zu niedrige Dosierungen machen das Produkt unwirksam, w\u00e4hrend zu hohe Dosierungen die menschliche Gesundheit sch\u00e4digen k\u00f6nnen. Aus diesem Grund wird im Rahmen der Produktqualit\u00e4tskontrolle eine <i>Bestimmung von Chlorhexidindigluconat<\/i> durchgef\u00fchrt. Diese Analyse:<\/span><\/p><ul><li><span style=\"color: #000000;\">confirms the active ingredient content of the product,<\/span><\/li><li><span style=\"color: #000000;\">ensures compliance with regulations and standards, and<\/span><\/li><li><span style=\"color: #000000;\">guarantees the effectiveness and safety of the product.<\/span><\/li><\/ul><h3><span style=\"color: #000000;\"><strong>IJPSR (2015) Method: Determination of chlorhexidine digluconate by HPLC<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">Die 2015 im <i>International Journal of Pharmaceutical Sciences and Research (<a href=\"https:\/\/ijpsr.com\/\">IJPSR<\/a>), Band 6, Ausgabe 12<\/i> ver\u00f6ffentlichte Methodik beschreibt eine analytische Bestimmungsmethode auf Basis der <i>Heavy Duty Liquid Chromatography (HPLC)<\/i>. Diese Methode wurde entwickelt, um den Chlorhexidin-Gehalt in CHX-haltigen bioziden L\u00f6sungen oder Produkten mit hoher Genauigkeit zu bestimmen.<\/span><\/p><p><span style=\"color: #000000;\"><strong>Analysis principle and basic properties:<\/strong><\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f Verwendung eines <i>HPLC-UV\/DAD<\/i>-Detektorsystems<\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f CHX standards are prepared in a certain concentration range<\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f The content is quantitatively measured with linear calibration curves<\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f The dissolved samples are separated with a suitable mobile phase<\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f UV detection at a wavelength of 254 nm<\/span><\/p><p><span style=\"color: #000000;\">\u2714\ufe0f The data are evaluated during the analysis using software (e.g., Empower)<\/span><\/p><p><span style=\"color: #000000;\">Diese Art von chromatographischen Methoden gew\u00e4hrleistet <i>hohe Genauigkeit, Wiederholbarkeit und Pr\u00e4zision<\/i> und wird daher in Qualit\u00e4tskontrolllabors f\u00fcr Routineanalysen bevorzugt.<\/span><\/p><h3><span style=\"color: #000000;\"><strong>Application areas of CHX analysis methods<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">This type of determination methods is not only applied theoretically in the laboratory but also used daily in the quality control of real products. In particular:<\/span><\/p><ul><li><span style=\"color: #000000;\">Detection of active ingredients in biocidal solutions<\/span><\/li><li><span style=\"color: #000000;\">Quality testing after the production of disinfectants<\/span><\/li><li><span style=\"color: #000000;\">Control processes by manufacturers and supervisory authorities<\/span><\/li><li><span style=\"color: #000000;\">Use as a reference method in accredited laboratories<\/span><\/li><\/ul><h3><span style=\"color: #000000;\"><strong>Analytical accuracy for quality and safety<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">Chlorhexidindigluconat ist ein starkes Antiseptikum, jedoch ist die Anwendung <i>standardisierter Analysemethoden<\/i> erforderlich, um diese Wirksamkeit in Produkten korrekt nachzuweisen. Die IJPSR-2015-Methodik erm\u00f6glicht die schnelle und zuverl\u00e4ssige Messung von CHX in bioziden Produkten mittels <b>HPLC-basierter SHG-Bestimmung<\/b>.<\/span><\/p><p><span style=\"color: #000000;\">Such analyses are important for both regulatory compliance and human health.<\/span><\/p><p><span style=\"color: #000000;\">Contact us! info@nano-test.de<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>CIPAC 36 Chlorhexidindigluconat-Bestimmung: Analytischer Ansatz und Bedeutung Chlorhexidindigluconat (CHX) ist ein Biozid, das aufgrund seiner starken antimikrobiellen und antiseptischen Eigenschaften sowohl in medizinischen als auch in Hygieneprodukten weit verbreitet ist. Aufgrund seiner Wirksamkeit insbesondere gegen grampositive und gramnegative Bakterien wird dieser Wirkstoff in Desinfektionsl\u00f6sungen, chirurgischen Antiseptika und Mundpflegeprodukten verwendet. Die korrekte Bestimmung der Wirkstoffmenge in \u2026 <a href=\"https:\/\/nano-test.de\/en\/2026\/03\/01\/chlorhexidindigluconat-bestimmung-cipac-36-und-ijpsr\/\" class=\"more-link\" title=\"Continue reading &amp;lt;span class=\" screen-reader-text>Chlorhexidindigluconat-Bestimmung: CIPAC 36 und IJPSR\u201c&gt;Continue reading <span class=\"screen-reader-text\">Chlorhexidine digluconate determination: CIPAC 36 and IJPSR<\/span><\/a><\/p>\n","protected":false},"author":4,"featured_media":4109,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-4108","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biozid-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Chlorhexidindigluconat-Bestimmung: CIPAC 36 und IJPSR | Nano-Test\u00ae<\/title>\n<meta name=\"description\" content=\"Pr\u00e4zise Bestimmung von Chlorhexidindigluconat mit HPLC gem\u00e4\u00df CIPAC 36 &amp; IJPSR 2015. 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