{"id":3962,"date":"2026-01-11T10:23:22","date_gmt":"2026-01-11T10:23:22","guid":{"rendered":"https:\/\/nano-test.de\/?p=3962"},"modified":"2026-01-11T10:32:53","modified_gmt":"2026-01-11T10:32:53","slug":"hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439","status":"publish","type":"post","link":"https:\/\/nano-test.de\/en\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/","title":{"rendered":"Skin irritation and corrosion toxicity tests: OECD Guidance 439"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"3962\" class=\"elementor elementor-3962\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4d65c52b ts-col-stretched-none ts-bg-color-over-image elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4d65c52b\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-39385d1e ts-bg-color-over-image\" data-id=\"39385d1e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4ad90e58 elementor-widget elementor-widget-text-editor\" data-id=\"4ad90e58\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2>Skin irritation and corrosion toxicity tests: OECD Guidance 439<\/h2><p><span style=\"color: #000000;\">The safety assessment of products that come into direct contact with the skin is essential for reasons of legal compliance, especially with regard to human health. At the top of these assessments are skin irritation and corrosion toxicity tests.<\/span><br><span style=\"color: #000000;\">The OECD 439 skin irritation test, developed as an alternative to animal testing, is often preferred due to its scientific validity and regulatory compliance.<\/span><\/p><h3><span style=\"color: #000000;\">What is OECD 439?<\/span><\/h3><p><span style=\"color: #000000;\">OECD 439 is an in vitro test guide designed to evaluate the skin irritation potential of chemicals and products. <\/span><span style=\"color: #000000;\">The test is performed using reconstituted human epidermis (RhE) models that mimic the human epidermis.<\/span><\/p><p><span style=\"color: #000000;\">This method offers a reliable alternative, especially in areas where animal testing is restricted or prohibited.<\/span><\/p><h3><span style=\"color: #000000;\">The difference between skin irritation and corrosion<\/span><\/h3><p><span style=\"color: #000000;\">Skin irritation: Reversible redness, swelling and irritation of the skin<\/span><br><span style=\"color: #000000;\">Skin corrosion: irreversible tissue damage that penetrates into the lower layers of the skin<\/span><br><span style=\"color: #000000;\">OECD 439 is used to determine irritation, while corrosion assessment is usually supported by methods such as OECD 430, 431 or 435.<\/span><\/p><h3><span style=\"color: #000000;\">Application steps of the OECD 439 test method<\/span><\/h3><ul><li><span style=\"color: #000000;\">Application of the <\/span><\/li><li><span style=\"color: #000000;\">Test substance on the RhE model<\/span><\/li><li><span style=\"color: #000000;\">Removing the sample after the specified contact time has elapsed<\/span><\/li><li><span style=\"color: #000000;\">Measurement of cell viability by metabolic tests<\/span><\/li><li><span style=\"color: #000000;\">Evaluation of results against thresholds<\/span><\/li><li><span style=\"color: #000000;\">The determined cell viability rates determine whether the product is classified as skin irritant or not.<\/span><\/li><\/ul><h3><span style=\"color: #000000;\">What products is OECD 439 used for?<\/span><\/h3><ul><li><span style=\"color: #000000;\"><a href=\"https:\/\/nano-test.de\/en\/service\/kosmetik\/\">Kosmetika<\/a> und K\u00f6rperpflegeprodukte<\/span><\/li><li><span style=\"color: #000000;\">Biocidal products<\/span><\/li><li><span style=\"color: #000000;\">Reinigungs- und <a href=\"https:\/\/nano-test.de\/en\/service\/waschmittel-und-seife-analysen\/\">Detergent<\/a><\/span><\/li><li><span style=\"color: #000000;\">Industrial Chemicals<\/span><\/li><li><span style=\"color: #000000;\">Stoffe, die mit <a href=\"https:\/\/nano-test.de\/en\/service\/medizinprodukt\/\">medizinischen Ger\u00e4ten<\/a> in <\/span><\/li><li><span style=\"color: #000000;\">Contact us<\/span><br><span style=\"color: #000000;\">In this respect, OECD 439 forms the basis for safety assessment in numerous industries.<\/span><\/li><\/ul><h3><span style=\"color: #000000;\">Benefits of the OECD 439 Test<\/span><\/h3><ul><li><span style=\"color: #000000;\">Alternative to animal testing and ethical approach<\/span><\/li><li><span style=\"color: #000000;\">High repeatability<\/span><\/li><li><span style=\"color: #000000;\">Short test duration<\/span><\/li><li><span style=\"color: #000000;\">Cost-effective solution<\/span><\/li><li><span style=\"color: #000000;\">Internationally recognized method<\/span><\/li><\/ul><p><span style=\"color: #000000;\">Der <a href=\"https:\/\/www.oecd.org\/content\/dam\/oecd\/en\/publications\/reports\/2021\/06\/test-no-439-in-vitro-skin-irritation-reconstructed-human-epidermis-test-method_g1g59b2f\/9789264242845-en.pdf\">OECD 439<\/a> Hautirritationstest ist ein wichtiger Bestandteil der modernen Toxikologie und bietet eine wissenschaftliche und gesetzeskonforme Bewertung zum Schutz der menschlichen Gesundheit.<\/span><\/p><p><span style=\"color: #000000;\">Please contact us for all the test details, the requirements for the approval of your products, and the full process<\/span>.<\/p><p><span style=\"color: #000000;\">info@nano-test.de<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Hautreizungs- und Korrosionstoxizit\u00e4tstests: OECD-Leitfaden 439 Die Sicherheitsbewertung von Produkten, die in direkten Kontakt mit der Haut kommen, ist aus Gr\u00fcnden der gesetzlichen Konformit\u00e4t, insbesondere im Hinblick auf die menschliche Gesundheit, unerl\u00e4sslich. An erster Stelle dieser Bewertungen stehen Hautirritations- und Korrosionstoxizit\u00e4tstests. Der OECD 439-Hautreizungstest, der als Alternative zu Tierversuchen entwickelt wurde, wird aufgrund seiner wissenschaftlichen Validit\u00e4t \u2026 <a href=\"https:\/\/nano-test.de\/en\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/\" class=\"more-link\" title=\"Continue reading &amp;lt;span class=\" screen-reader-text>Hautreizungs- und Korrosionstoxizit\u00e4tstests: OECD-Leitfaden 439\u201c&gt;Continue reading <span class=\"screen-reader-text\">Skin irritation and corrosion toxicity tests: OECD Guidance 439<\/span><\/a><\/p>\n","protected":false},"author":4,"featured_media":3964,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-3962","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kozmetik-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hautreizungs- und Korrosionstoxizit\u00e4tstests: OECD-Leitfaden 439 | Nano-Test\u00ae<\/title>\n<meta name=\"description\" content=\"Was ist OECD 439? Detaillierte Informationen \u00fcber die OECD 439-Testmethode, die zur Bewertung der Hautreizung und Korrosionstoxizit\u00e4t verwendet wird, den In-vitro-Ansatz und die rechtliche Bedeutung.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hautreizungs- und Korrosionstoxizit\u00e4tstests: OECD-Leitfaden 439 | Nano-Test\u00ae\" \/>\n<meta property=\"og:description\" content=\"Was ist OECD 439? Detaillierte Informationen \u00fcber die OECD 439-Testmethode, die zur Bewertung der Hautreizung und Korrosionstoxizit\u00e4t verwendet wird, den In-vitro-Ansatz und die rechtliche Bedeutung.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/\" \/>\n<meta property=\"og:site_name\" content=\"Nano-Test\u00ae\" \/>\n<meta property=\"article:published_time\" content=\"2026-01-11T10:23:22+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-11T10:32:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nano-test.de\/wp-content\/uploads\/2026\/01\/Hautreizungs-und-Korrosionstoxizitaetstests-OECD-Leitfaden-439.png\" \/>\n\t<meta property=\"og:image:width\" content=\"750\" \/>\n\t<meta property=\"og:image:height\" content=\"450\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Sultan Culum\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Sultan Culum\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/\"},\"author\":{\"name\":\"Sultan Culum\",\"@id\":\"https:\\\/\\\/nano-test.de\\\/#\\\/schema\\\/person\\\/e873a4aee4023b424d94f10e41a12670\"},\"headline\":\"Hautreizungs- und Korrosionstoxizit\u00e4tstests: OECD-Leitfaden 439\",\"datePublished\":\"2026-01-11T10:23:22+00:00\",\"dateModified\":\"2026-01-11T10:32:53+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/\"},\"wordCount\":336,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/nano-test.de\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/nano-test.de\\\/wp-content\\\/uploads\\\/2026\\\/01\\\/Hautreizungs-und-Korrosionstoxizitaetstests-OECD-Leitfaden-439.png\",\"articleSection\":[\"Kosmetik\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/\",\"url\":\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/\",\"name\":\"Hautreizungs- und Korrosionstoxizit\u00e4tstests: OECD-Leitfaden 439 | Nano-Test\u00ae\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/nano-test.de\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/nano-test.de\\\/wp-content\\\/uploads\\\/2026\\\/01\\\/Hautreizungs-und-Korrosionstoxizitaetstests-OECD-Leitfaden-439.png\",\"datePublished\":\"2026-01-11T10:23:22+00:00\",\"dateModified\":\"2026-01-11T10:32:53+00:00\",\"description\":\"Was ist OECD 439? Detaillierte Informationen \u00fcber die OECD 439-Testmethode, die zur Bewertung der Hautreizung und Korrosionstoxizit\u00e4t verwendet wird, den In-vitro-Ansatz und die rechtliche Bedeutung.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/#primaryimage\",\"url\":\"https:\\\/\\\/nano-test.de\\\/wp-content\\\/uploads\\\/2026\\\/01\\\/Hautreizungs-und-Korrosionstoxizitaetstests-OECD-Leitfaden-439.png\",\"contentUrl\":\"https:\\\/\\\/nano-test.de\\\/wp-content\\\/uploads\\\/2026\\\/01\\\/Hautreizungs-und-Korrosionstoxizitaetstests-OECD-Leitfaden-439.png\",\"width\":750,\"height\":450,\"caption\":\"Nano-Test.de erkl\u00e4rt Hautreizungs- und Korrosionstoxizit\u00e4tstests nach OECD 439, um die Sicherheit von kosmetischen und chemischen Produkten zu gew\u00e4hrleisten\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/nano-test.de\\\/2026\\\/01\\\/11\\\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/nano-test.de\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Hautreizungs- und Korrosionstoxizit\u00e4tstests: OECD-Leitfaden 439\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/nano-test.de\\\/#website\",\"url\":\"https:\\\/\\\/nano-test.de\\\/\",\"name\":\"NANO-TEST\u00ae\",\"description\":\"Laboranalysen, Testservices, Pr\u00fcflabor &amp; Qualit\u00e4tskontrollen in Deutschland\",\"publisher\":{\"@id\":\"https:\\\/\\\/nano-test.de\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/nano-test.de\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/nano-test.de\\\/#organization\",\"name\":\"NANO-TEST\u00ae\",\"url\":\"https:\\\/\\\/nano-test.de\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/nano-test.de\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/nano-test.de\\\/wp-content\\\/uploads\\\/2026\\\/03\\\/Nanotest-Logo-NT-scaled.png\",\"contentUrl\":\"https:\\\/\\\/nano-test.de\\\/wp-content\\\/uploads\\\/2026\\\/03\\\/Nanotest-Logo-NT-scaled.png\",\"width\":2510,\"height\":2560,\"caption\":\"NANO-TEST\u00ae\"},\"image\":{\"@id\":\"https:\\\/\\\/nano-test.de\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/nano-test.de\\\/#\\\/schema\\\/person\\\/e873a4aee4023b424d94f10e41a12670\",\"name\":\"Sultan Culum\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ef47288e2a0dc3ff55e71e172f39c9c82ffbf55bad226f89d1aaa823e517a73b?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ef47288e2a0dc3ff55e71e172f39c9c82ffbf55bad226f89d1aaa823e517a73b?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ef47288e2a0dc3ff55e71e172f39c9c82ffbf55bad226f89d1aaa823e517a73b?s=96&d=mm&r=g\",\"caption\":\"Sultan Culum\"},\"sameAs\":[\"https:\\\/\\\/nano-test.de\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Skin irritation and corrosion toxicity tests: OECD Guidance 439 | Nano Test\u00ae","description":"What is OECD 439? Detailed information about the OECD 439 test method used to assess skin irritation and corrosion toxicity, the in vitro approach and the legal significance.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/","og_locale":"en_US","og_type":"article","og_title":"Hautreizungs- und Korrosionstoxizit\u00e4tstests: OECD-Leitfaden 439 | Nano-Test\u00ae","og_description":"Was ist OECD 439? Detaillierte Informationen \u00fcber die OECD 439-Testmethode, die zur Bewertung der Hautreizung und Korrosionstoxizit\u00e4t verwendet wird, den In-vitro-Ansatz und die rechtliche Bedeutung.","og_url":"https:\/\/nano-test.de\/en\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/","og_site_name":"Nano-Test\u00ae","article_published_time":"2026-01-11T10:23:22+00:00","article_modified_time":"2026-01-11T10:32:53+00:00","og_image":[{"width":750,"height":450,"url":"https:\/\/nano-test.de\/wp-content\/uploads\/2026\/01\/Hautreizungs-und-Korrosionstoxizitaetstests-OECD-Leitfaden-439.png","type":"image\/png"}],"author":"Sultan Culum","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Sultan Culum","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/#article","isPartOf":{"@id":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/"},"author":{"name":"Sultan Culum","@id":"https:\/\/nano-test.de\/#\/schema\/person\/e873a4aee4023b424d94f10e41a12670"},"headline":"Hautreizungs- und Korrosionstoxizit\u00e4tstests: OECD-Leitfaden 439","datePublished":"2026-01-11T10:23:22+00:00","dateModified":"2026-01-11T10:32:53+00:00","mainEntityOfPage":{"@id":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/"},"wordCount":336,"commentCount":0,"publisher":{"@id":"https:\/\/nano-test.de\/#organization"},"image":{"@id":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/#primaryimage"},"thumbnailUrl":"https:\/\/nano-test.de\/wp-content\/uploads\/2026\/01\/Hautreizungs-und-Korrosionstoxizitaetstests-OECD-Leitfaden-439.png","articleSection":["Kosmetik"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/","url":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/","name":"Skin irritation and corrosion toxicity tests: OECD Guidance 439 | Nano Test\u00ae","isPartOf":{"@id":"https:\/\/nano-test.de\/#website"},"primaryImageOfPage":{"@id":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/#primaryimage"},"image":{"@id":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/#primaryimage"},"thumbnailUrl":"https:\/\/nano-test.de\/wp-content\/uploads\/2026\/01\/Hautreizungs-und-Korrosionstoxizitaetstests-OECD-Leitfaden-439.png","datePublished":"2026-01-11T10:23:22+00:00","dateModified":"2026-01-11T10:32:53+00:00","description":"What is OECD 439? Detailed information about the OECD 439 test method used to assess skin irritation and corrosion toxicity, the in vitro approach and the legal significance.","breadcrumb":{"@id":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/#primaryimage","url":"https:\/\/nano-test.de\/wp-content\/uploads\/2026\/01\/Hautreizungs-und-Korrosionstoxizitaetstests-OECD-Leitfaden-439.png","contentUrl":"https:\/\/nano-test.de\/wp-content\/uploads\/2026\/01\/Hautreizungs-und-Korrosionstoxizitaetstests-OECD-Leitfaden-439.png","width":750,"height":450,"caption":"Nano-Test.de explains skin irritation and corrosion toxicity tests according to OECD 439 to ensure the safety of cosmetic and chemical products"},{"@type":"BreadcrumbList","@id":"https:\/\/nano-test.de\/2026\/01\/11\/hautreizungs-und-korrosionstoxizitaetstests-oecd-leitfaden-439\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/nano-test.de\/"},{"@type":"ListItem","position":2,"name":"Skin irritation and corrosion toxicity tests: OECD Guidance 439"}]},{"@type":"WebSite","@id":"https:\/\/nano-test.de\/#website","url":"https:\/\/nano-test.de\/","name":"NANO-TEST\u00ae","description":"Laboratory analyses, testing services, testing laboratories and quality control in Germany","publisher":{"@id":"https:\/\/nano-test.de\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/nano-test.de\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/nano-test.de\/#organization","name":"NANO-TEST\u00ae","url":"https:\/\/nano-test.de\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/nano-test.de\/#\/schema\/logo\/image\/","url":"https:\/\/nano-test.de\/wp-content\/uploads\/2026\/03\/Nanotest-Logo-NT-scaled.png","contentUrl":"https:\/\/nano-test.de\/wp-content\/uploads\/2026\/03\/Nanotest-Logo-NT-scaled.png","width":2510,"height":2560,"caption":"NANO-TEST\u00ae"},"image":{"@id":"https:\/\/nano-test.de\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/nano-test.de\/#\/schema\/person\/e873a4aee4023b424d94f10e41a12670","name":"Sultan Culum","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/ef47288e2a0dc3ff55e71e172f39c9c82ffbf55bad226f89d1aaa823e517a73b?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/ef47288e2a0dc3ff55e71e172f39c9c82ffbf55bad226f89d1aaa823e517a73b?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/ef47288e2a0dc3ff55e71e172f39c9c82ffbf55bad226f89d1aaa823e517a73b?s=96&d=mm&r=g","caption":"Sultan Culum"},"sameAs":["https:\/\/nano-test.de"]}]}},"_links":{"self":[{"href":"https:\/\/nano-test.de\/wp-json\/wp\/v2\/posts\/3962","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nano-test.de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nano-test.de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nano-test.de\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/nano-test.de\/wp-json\/wp\/v2\/comments?post=3962"}],"version-history":[{"count":0,"href":"https:\/\/nano-test.de\/wp-json\/wp\/v2\/posts\/3962\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nano-test.de\/wp-json\/wp\/v2\/media\/3964"}],"wp:attachment":[{"href":"https:\/\/nano-test.de\/wp-json\/wp\/v2\/media?parent=3962"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nano-test.de\/wp-json\/wp\/v2\/categories?post=3962"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nano-test.de\/wp-json\/wp\/v2\/tags?post=3962"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}