{"id":2971,"date":"2025-06-27T18:51:02","date_gmt":"2025-06-27T18:51:02","guid":{"rendered":"https:\/\/nano-test.de\/?p=2971"},"modified":"2025-07-01T10:19:21","modified_gmt":"2025-07-01T10:19:21","slug":"in-vivo-tests-von-tierarzneimitteln-im-rahmen-der-glp","status":"publish","type":"post","link":"https:\/\/nano-test.de\/en\/2025\/06\/27\/in-vivo-tests-von-tierarzneimitteln-im-rahmen-der-glp\/","title":{"rendered":"In-vivo tests of veterinary medicinal products within the framework of the GLP"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2971\" class=\"elementor elementor-2971\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-01ae11c ts-col-stretched-none ts-bg-color-over-image elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"01ae11c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fd71a18 ts-bg-color-over-image\" data-id=\"fd71a18\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8b2933a elementor-widget elementor-widget-text-editor\" data-id=\"8b2933a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #000000;\">Die Tiergesundheit ist sowohl f\u00fcr die Nachhaltigkeit der Landwirtschaft und der Lebensmittelindustrie als auch f\u00fcr die \u00f6ffentliche Gesundheit von gro\u00dfer Bedeutung. Der Nachweis der Wirksamkeit und Sicherheit von Tierarzneimitteln erfordert jedoch, dass diese Produkte vor ihrer Markteinf\u00fchrung getestet werden. In diesem Zusammenhang sind <a href=\"https:\/\/nano-test.de\/en\/research\/in-vivo-tests\/\"><b>In vivo tests<\/b><\/a>, die im Rahmen der <b>Guten Laborpraxis (GLP)<\/b> durchgef\u00fchrt werden, ein unverzichtbarer Bestandteil der Entwicklung von Tierarzneimitteln.<\/span><\/p><blockquote><h3><span style=\"color: #000000;\"><strong>What are in vivo tests for veterinary medicines?<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">In-vivo tests are studies in which veterinary medicinal products are used on live animals to assess parameters such as efficacy, safety and bioavailability. These tests determine whether the drug has the desired effect and what possible side effects can occur.<\/span><\/p><h3>\u00a0<\/h3><\/blockquote><h3><span style=\"color: #000000;\"><strong>What is GLP and why is it important?<\/strong><\/span><\/h3><p><span style=\"color: #000000;\"><b><a href=\"https:\/\/nano-test.de\/en\/service\/gute-laborpraxis-glp\/\">GLP (Gute Laborpraxis<\/a>)<\/b> ist ein internationaler Qualit\u00e4tsstandard f\u00fcr die Planung, Durchf\u00fchrung, \u00dcberwachung, Aufzeichnung, Berichterstattung und Archivierung von Arbeiten in Laboratorien. GLP gew\u00e4hrleistet Transparenz und Genauigkeit insbesondere bei kritischen Tests wie Sicherheitsbewertungen.<\/span><\/p><p><span style=\"color: #000000;\">Veterinary Medicines Tests performed according to GLP standards:<\/span><\/p><ul><li><span style=\"color: #000000;\">Ensure scientific validity<\/span><\/li><li><span style=\"color: #000000;\">They are recognized by national and international supervisory authorities<\/span><\/li><li><span style=\"color: #000000;\">They speed up approval procedures<\/span><\/li><li><span style=\"color: #000000;\">Minimize animal health and public health risks<\/span><\/li><\/ul><h3><span style=\"color: #000000;\"><strong>Main In-Vivo Tests for Veterinary Medicines<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">In the development process of veterinary medicinal products, various in-vivo tests are carried out for different purposes:<\/span><\/p><p><span style=\"color: #000000;\">\ud83d\udd2c <b>Efficacy tests:<\/b> Die Wirksamkeit des Arzneimittels gegen\u00fcber der Zielkrankheit oder -infektion wird gemessen.<\/span><\/p><p><span style=\"color: #000000;\">\ud83d\udd2c <b>Toxizit\u00e4tstests:<\/b> Durch die Bewertung der akuten, subchronischen oder chronischen Toxizit\u00e4t wird das Sicherheitsprofil des Arzneimittels bestimmt.<\/span><\/p><p><span style=\"color: #000000;\">\ud83d\udd2c <b>Pharmakokinetische und Bioverf\u00fcgbarkeitsstudien:<\/b> Die Resorption, Verteilung, Metabolisierung und Ausscheidung des Arzneimittels im K\u00f6rper werden untersucht.<\/span><\/p><p><span style=\"color: #000000;\">\ud83d\udd2c <b>Sicherheitstests an Zieltierarten:<\/b> Die m\u00f6glichen Nebenwirkungen des Arzneimittels bei der Zieltierart werden bewertet.<\/span><\/p><p><span style=\"color: #000000;\">\ud83d\udd2c <b>Environmental compatibility tests:<\/b> Die potenziellen negativen Auswirkungen des Arzneimittels auf die Umwelt werden untersucht.<\/span><\/p><p><span style=\"color: #000000;\">Performing all these tests in accordance with GLP standards increases the reliability and legal acceptance of the data obtained.<\/span><\/p><h3><span style=\"color: #000000;\"><strong>Why are in vivo tests required?<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">In contrast to human medicines, veterinary medicines have effects on food safety, environmental health and zoonotic diseases in addition to animal health.<\/span><\/p><ul><li><span style=\"color: #000000;\">Preventing unexpected side effects in animals<\/span><\/li><li><span style=\"color: #000000;\">Preventing serious problems such as antibiotic resistance<\/span><\/li><li><span style=\"color: #000000;\">Safety of animal products such as meat, milk and eggs<\/span><\/li><li><span style=\"color: #000000;\">Determination of possible negative effects on the environment<\/span><\/li><li><span style=\"color: #000000;\">Compliance with legal regulations in the phases of approval and market launch<\/span><\/li><\/ul><h3><span style=\"color: #000000;\"><strong>GLP standards for safe veterinary medicines<\/strong><\/span><\/h3><p><span style=\"color: #000000;\">In-vivo tests within the framework of the GLP are a scientific and legal obligation that indirectly serves human health. Reliable data obtained with GLP-compliant tests is the most important proof of the effectiveness and safety of products.<\/span><\/p><p><span style=\"color: #000000;\">If you would like to have reliable in-vivo tests carried out as part of the registration procedures for your veterinary medicines, you can rely on our competent laboratory services.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Die Tiergesundheit ist sowohl f\u00fcr die Nachhaltigkeit der Landwirtschaft und der Lebensmittelindustrie als auch f\u00fcr die \u00f6ffentliche Gesundheit von gro\u00dfer Bedeutung. Der Nachweis der Wirksamkeit und Sicherheit von Tierarzneimitteln erfordert jedoch, dass diese Produkte vor ihrer Markteinf\u00fchrung getestet werden. In diesem Zusammenhang sind In-vivo-Tests, die im Rahmen der Guten Laborpraxis (GLP) durchgef\u00fchrt werden, ein unverzichtbarer \u2026 <a href=\"https:\/\/nano-test.de\/en\/2025\/06\/27\/in-vivo-tests-von-tierarzneimitteln-im-rahmen-der-glp\/\" class=\"more-link\" title=\"Continue reading &amp;lt;span class=\" screen-reader-text>In-vivo-Tests von Tierarzneimitteln im Rahmen der GLP\u201c&gt;Continue reading <span class=\"screen-reader-text\">In-vivo tests of veterinary medicinal products within the framework of the GLP<\/span><\/a><\/p>\n","protected":false},"author":4,"featured_media":2972,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-2971","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-glp-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - 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